Cap написал(а):
Хотя бы самое-самое общее описание методологий пары-тройки таких экспериментов - можно?
Тут я, канеш, извиняюсь, но "я за вас свою работу делать не буду" :lol:
В качестве примера
Oral L-carnitine combined with training promotes changes in skeletal muscle.
Rivero JL, Sporleder HP, Quiroz-Rothe E, Vervuert I, Coenen M, Harmeyer J.
Department of Anatomy, University of Cordoba, Spain.
The purpose of this study was to determine whether oral L-carnitine supplementation enhances the responses of skeletal muscle to training in seven 2-year-old Standardbreds. Four horses were supplemented with 10 g/day L-carnitine for 10 weeks and 3 horses served as controls. All horses were exercised regularly every second day on a treadmill for 5 weeks (training period) and housed in individual boxes for 5 additional weeks (detraining period). The training period consisted of 8 high- and 8 low-speed exercises carried out in alternating sequence. Gluteus medius muscle biopsies were taken at Weeks 0 (pretraining), 5 (post-training) and 10 (detraining). Muscular adaptations to training were observed mainly in the L-carnitine-supplemented horses and included an increase in the percentage of type IIA fibres (delta35%, P<0.05), atrophy of type I fibres (delta24%, P<0.01), a rise in the capillary-to-fibre ratio (delta40%, P<0.01) and an increase in the quantitative reaction of periodic acid Schiff stain (delta11%, P<0.05), used as an indicator of intrafibre glycogen content. After detraining, most of these adaptations reverted towards the pretraining situation. Therefore, exogenous carnitine has an additive effect on muscular responses to training and this should be favourable to improve athletic performance.
Про витамин Е
Mäenpää et al. (1988) observed seasonal differences in serum alpha-tocopherol concentrations in mares and foals kept on pasture from early June until early October, then fed timothy hay and oats through the winter. Serum alpha tocopherol concentrations were highest in August and September (2.7 µg/ml for mares and 2.1 µg/ml for foals) and lowest in April or May (1.5 µg/ml for mares and 1.2 µg/ml for foals) after being fed hay during the winter months. When mares were given winter supplements of 100 to 400 IU of vitamin E/day, no significant increases in serum alpha-tocopherol concentrations occurred and seasonal differences persisted. However, when foals were supplemented with 400 IU vitamin E daily during winter months, serum alpha-tocopherol concentrations increased from 1.3 µg/ml to approximately 2 µg/ml in April and May. Blakley and Bell (1994) observed similar seasonal variation in plasma vitamin E
Janssen and Ullrey (1986) observed that the capture and restraint of zebra and Przewalski horses for hoof trimming resulted in temporary to persistent muscle soreness and lameness. They found that plasma alpha-tocopherol concentrations
were commonly below 1 µg/ml in animals consuming diets supplemented with 50 IU vitamin E/kg DM. When supplemental levels were increased to 100 IU/kg DM, no signs of muscle pathology were seen, and plasma alpha-tocopherol concentrations ranged from 1.5 to 3 µg/ml after increasing vitamin E supplemental levels.
По витамину Е могу также сказать на собственном опыте - у 4 лошадей на конюшенном содержании витамин Е в сыворотке пришел в норму после полугода кормления синтетическим витамином Е в масле в количестве 1600-2000 МЕ в день (мож и раньше пришел, просто я кровь раз в полгода сдаю
))
Остальное Вы, как человек пытливый, думаю, сами как-нибудь :wink: Разжевать и в рот положить - это же не наш метод, правда? :lol:
